Tesamorelin, is a growth-hormone-releasing hormone (GHRH) analogue used clinically for the treatment of HIV-associated lipodystrophy. (In lipodystrophy, fat accumulates excessively both in the abdomen and in other areas of the body.) It is also being researched for its ability to improve peripheral nerve health, slow the progression of mild cognitive impairment/dementia, and the reduction fat mass..